1 = Focally increased between lobules |
1 = Periductal necrosis (<5%) |
1 = In ducts (around ductal margins) |
1 = In the parenchyma bleeding (0–25%) |
2 = Diffusely increased between lobules |
2 = Focal necrosis (5–20%) |
2 = In the parenchyma (in <50% of the lobules) |
2 = In the parenchyma bleeding (25–50%) |
3 = Acini disrupted and separated |
3 = Diffuse parenchymal necrosis (20–50%) |
3 = In the parenchyma (in 50–75% of the lobules) |
3 = In the parenchyma bleeding (50–75%) |
4 = Obvious lobules separated |
4 = Diffuse parenchymal necrosis >50% |
4 = In the parenchyma (>75% of the lobules) |
4 = In the parenchyma bleeding >75 |