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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2016 Jul 20;9(1):10.1002/wnan.1420. doi: 10.1002/wnan.1420

Fig. 4. Photoacoustic images of a mouse bearing a HT29 tumor before and after intravascular injection of SiNc. Greyscale background is overlaid with the signal from SiNc (hot scale).

Fig. 4

A) Pre-injection image, indicating tumor (dashed white circle) and surrounding blood vessels (BV, dotted red circles), overlaid with deoxygenated (blue scale) and oxygenated (red scale) hemoglobin signal. (B–F) Images acquired after 5 (B), 15 (C), 30 (D), 45 (E), 60 (F) minutes after intravenous injection of SiNc in a tumor-bearing animal. Reproduced with publisher permission.36