Table 2.

Total, Direct, and Indirect Effects of Body Mass Index on Recurrent Gout Attacks among All Participants without Gout at Baseline

BMI Categories	Follow-up time (PY)	N of People with Recurrent Gout Attacks	Recurrent Gout Attacks Rate (per 1000 PY)	Total Effect OR* (95% CI)	Indirect Effect OR* (95% CI)	Direct Effect OR* (95% CI)
Normal	15,209	14	0.92	1.0	1.0	1.0
Overweight	39,344	73	1.86	1.98 (1.12, 3.51)	1.57 (1.17, 2.21)	1.27 (0.98, 1.64)
Obese	16,530	44	2.66	2.75 (1.50, 5.04)	2.83 (2.17, 3.67)	0.98 (0.71, 1.34)

^*Adjusted for baseline age, education, alcohol and coffee intake, presence of hypertension, and diuretic use PY=Person-years