Table 5. Duration and number of EBD sessions.
Prophylactic treatment | P value | ||||||
No treatment | Steroid injection | Steroid injection followed by oral steroid | Total | No treatment vs. steroid injection | No treatment vs. steroid injection followed by oral steroid | Steroid injection vs. steroid injection followed by oral steroid | |
n = 14 | n = 30 | n = 24 | n = 68 | ||||
Case of stricture | 14 | 19 | 12 | 45 | |||
Time to achieve EBD success (days) median (IQR) | 173 (85.8 – 230) | 84 (53.5 – 123) | 92.5 (64.3 – 129) | 92 (66 – 176) | 0.58 | 0.053 | 0.26 |
Number of EBD sessions median (IQR) | 12.5 (7.5 – 16) | 6 (4.5 – 10.5) | 5.5 (4 – 8.3) | 7 (5 – 12) | 0.046 | 0.002 | 0.51 |
1~2 | 0 | 4 | 2 | 6 | |||
3~5 | 2 | 5 | 4 | 11 | |||
≥ 6 | 12 | 10 | 6 | 28 | |||
Refractory stricture rate | 12/14 (86 %)(95 %CI: 57 – 98 %) | 10/30 (33 %)(95 %CI: 17 – 53 %) | 6/24 (25 %)(95 %CI: 10 – 47 %) | 28/68 (41 %)(95 %CI: 29 – 54 %) | 0.002 | < 0.001 | 0.56 |
EBD, endoscopic balloon dilation; IQR, interquartile range; 95 %CI, 95 % confidence interval. We analyzed data for Groups B and C without Group A, and excluded the 2 cases that could not be evaluated for whether they had refractory strictures.