Table 2. Performance of HEMA-EXPRESS test for active-TB diagnosis in the different study populations.
Population | TB prevalence (%) | Group | N | HEMA-EXPRESS positives | Sensitivity | Specificity | Accuracy | Positive predicting value | Negative predicting value |
---|---|---|---|---|---|---|---|---|---|
1 | 4.0 | Active TB | 9 | 7 | 77.8 | 97.2 | 96.4 | 53.8 | 99.0 |
Controls | 213 | 6 | |||||||
2 | 15.4 | Active TB | 60 | 35 | 58.3 | 97.3 | 91.3 | 79.5 | 92.8 |
Controls | 330 | 9 | |||||||
3 | 16.7 | Active TB | 51 | 36 | 70.5 | 51.6 | 54.7 | 22.6 | 89.7 |
Controls | 254 | 123 | |||||||
4 | 31.9 | Active TB | 15 | 2 | 13.3 | 53.1 | 40.4 | 11.8 | 56.7 |
Controls | 32 | 15 | |||||||
5 | 5.4 | Active TB | 3 | 2 | 66.6 | 96.1 | 94.5 | 50.0 | 98.0 |
Controls | 52 | 2 | |||||||
6 | 41.4 | Active TB | 152 | 6 | 3.9 | 94.4 | 56.9 | 33.3 | 58.2 |
Controls | 215 | 12 | |||||||
Total | 20.5 | Active TB | 290 | 88 | 30.6 | 84.6 | 73.5 | 34.0 | 82.5 |
Controls | 1,096 | 167 |
HEMA-EXPRESS, rapid 123 TB-XT HEMA EXPRESS test; TB, tuberculosis.