HSROC curve of WLB, AFB, AFB + WLB and NBI. The performance of NBI is remarkable, that of AFB and AFB + WLB is close. WLB showed the worse performance in single-arm synthesis. HSROC, hierarchical summary receiver operating characteristic; WLB, white light bronchoscopy; AFB, autofluorescence bronchoscopy; AFB + WLB, AFB combined with WLB; NBI, narrow-band imaging.