Table 3.

Genotype distribution of 101 isolates (one isolate per genotype per patient) according to the most frequent MSH2 genotype.

	Gt (n)	WT n (%)	E7K n (%)	P208S/N890I n (%)	E456D n (%)	V239L/A942T n (%)	V239L n (%)	Other n (%)
Frequent genotypes (5 genotypes, 41 isolates)	Gt1 (19)	15 (88)	3 (16)					1 (6) S346T
	Gt2 (4)	4 (100)
	Gt10 (5)					4 (80)		1 (10) V34E/V239L/A942T
	Gt18 (5)			5 (100)				1 (10) N890I/A942T*
	Gt30 (8)				8 (100)
Rare genotypes (44 genotypes, 60 isolates)	Gt4 (3)						3 (100)
	Gt32 (3)			3 (100)
	Gt36 (3)	2 (66.6)		1 (33.3)
	Gt45 (3)	3 (100)
	Gt3 (2)	2 (100)
	Gt5 (2)						2 (100)
	Gt6 (2)						2 (100)
	Gt7 (2)					2 (100)
	Gt8 (2)					2 (100)
	Gt22 (2)	1 (50)		1(50)
	Gt23 (2)	2 (100)
	Gt41 (2)						2 (100)
	Singletons (32)	19 (59)		7 (22)		2 (6)		1 (3) P208S/N890I/Y949C; 2 (6) M651T; 1 (3) E478Q

^*One isolates harboring Gt18 was a mixture of N890I/A942T and P208S/N890I sequences.