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COMT enzymatic activity in microsomes and extracellular vesicles obtained from primary rat hepatocytes.
| Sample | 3-MT (nmol/mg/hour)* |
|---|---|
| Microsomes t0 | 78.80 ± 4.04 |
| Microsomes t36 Control | 24.70 ± 0.36 |
| Microsomes t36 Diclofenac | 13.80 ± 0.03 |
| EVs t36 Control | 0.27 ± 0.02 |
| EVs t36 Diclofenac | 0.32 ± 0.03 |
mean ± SD, n = 3.
