Figure 8.
Supplementation with wild-type Prph2 does not rescue rod or cone function in Prph2KΔ/+. (A) Western blot analysis and quantification of Prph2, Rom1, rhodopsin and corresponding actin loading control are presented. (B–C) Amplitudes of scotopic a-wave, scotopic b-wave and photopic b-wave are shown from P30 (B) and P180 (C) of the indicated genotypes. (D–E) EM images are taken from P30 retinas of the indicated genotypes. Black brackets show OS length. Images in (E) are higher magnification of same genotypes as (D). Scale bars, 10 µm (D), 2 µm (E).