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. 2016 Sep 22;32(1):47–57. doi: 10.1093/mutage/gew046

Figure 2.

Figure 2.

Levels of DNA strand breaks in lung tissue from mice 1, 3 and 28 days after intratracheal instillation of NRCWE-001 and NRCWE-002. Levels of DNA strand breaks was measured by comet assay: (A) data shown as tail length (TL) and (B) data shown as %DNA in tail (%TDNA). The values represent single mouse measurement in three different post-exposure times (1, 3 and 28 days) after single administration of NRCWE-001 and NRCWE-002 (18, 54, 162 µg/animal) and vehicle controls. The values represent mean of all animals in the group ± SEM (n = 8–12). *P ˂ 0.05, **P ˂ 0.01, ***P ˂ 0.001: TL and %TDNA, respectively, in NRCWE-001 and NRCWE-002–treated group vs. vehicle controls.