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Pulmonary Saa3 mRNA expression levels with dose response effect in mice 1, 3 and 28 days after intratracheal instillation of NRCWE-001 and NRCWE-002. Saa3 mRNA levels were normalized to 18S RNA. The values represent mean of all animals in group ± SEM (n = 8–12). ***P ˂ 0.001: Saa3 mRNA expression level in TiO2 NP-treated group vs. vehicle controls.
