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. 2016 Dec 23;6:39424. doi: 10.1038/srep39424

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Copyright © 2016, The Author(s)

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(A) The amphiphilic surfaces of type I and II chains. Type I is found in chains A and D, and type II in chains B and C. All hydrophobic amino acid side chains are shown for both types. (B) The simulated process of tetramer formation via hydrophobic interaction. It begins from a dimer of chains A and D, chains C and B follow.