Table 3. Fisher’s exact test for comparisons of allele frequencies between patients and healthy controls for a set of genes associated with the innate immune system.
| Comparison | P-value | OR | OR 95% confidence interval |
|---|---|---|---|
| HC/VEO IBD | 0.01061 | 1.27 | 1.05–1.54 |
| HC/Adult IBD | 0.7369 | 1.03 | 0.85–1.26 |
| HC/VEO UC | 0.08641 | 1.2 | 0.97–1.48 |
| HC/VEO CD | 0.004451 | 1.34 | 1.09–1.66 |
| HC/Adult UC | 0.5968 | 0.94 | 0.77–1.17 |
| HC/Adult CD | 0.2206 | 1.14 | 0.92–1.42 |
| Adult IBD/VEO IBD | 0.0007325 | 1.23 | 1.09–1.39 |
| Adult CD/VEO CD | 0.06776 | 1.17 | 0.99–1.4 |
| Adult UC/VEO UC | 0.006933 | 1.27 | 1.07–1.51 |
HC: healthy controls; CD: Crohn’s disease; UC: ulcerative colitis; VEO: very early-onset; IBD: inflammatory bowel disease; OR: Odds ratio