Table 1. The list of DCEs between different mouse groups.

Age	DCEs (3×Tg-AD v.s. WT)		DCEs (Se-treated v.s. 3×Tg-AD)
	Increased	Decreased	Increased	Decreased
2-month	Fe, Zn, Cu, Cd, Pb, Bi, Hg	Co	—	—
4-month	Fe, Ca, Zn, Cd, Bi, Hg	—	Se	—
6-month	Fe, Zn, Cu, As, Bi, Hg	Mn	Se, As	—
8-month	Fe, Ca, Co, Zn, Cu, As, Cd, Hg	Mn, Se	Se, Cr	Fe, Zn, Mn, Cd, Bi
10-month	Fe, Ca, Co, Zn, Cu, Hg	Mn, Bi	Se, As	Fe, Zn
12-month	Zn, Cd, Bi, Hg	Mn	Mg	Fe, Zn, V