Table 1.
CMPD IDa | Chemical structure | IC50 (μM) | Scoreb kcal/mol | Glide Score c kcal/mol |
---|---|---|---|---|
15944862 | 5.9 | −9.4 | −9.6 | |
3167530 | 2.0 | −7.8 | −7.8 | |
5973599 | 5.5 | −7.2 | −7.5 | |
3186499 | 5.8 | −7.1 | −7.3 | |
5826369 | 7.2 | −6.9 | −6.9 | |
3185712 | 13.7 | −6.8 | −6.8 | |
1432744 | 17.1 | −6.8 | −6.9 | |
1919699 | 11.7 | −6.7 | −6.7 | |
7256141 | 9.1 | −6.7 | −6.7 | |
3185717 | 2.7 | −6.6 | −6.6 | |
1452563 | 0.6 | −6.6 | −6.6 | |
1107365 | 15.1 | −6.5 | −6.5 |
PubChem Compound ID (CID)
XP Docking Score (Epik penalties applied)
Glide XP Docking Score