Table 1.
A summary of the mosaic tetracycline genes reported to date
| Gene | Organism | Source(s) | Accession number | Reference(s) |
|---|---|---|---|---|
| tet(O/W) | Bifidobacterium thermophilum B0219 | environmental (pig slaughterhouse) sample | AM889118 | 32 |
| tet(O/W) | B. thermophilum B0241 | pig faeces | AM889119 | 32 |
| tet(O/W) | B. thermophilum B0242 | pig faeces | AM889120 | 32 |
| tet(O/W) | B. thermophilum B0253 | pig faeces | AM889121 | 32 |
| tet(O/W) | B. thermophilum B0256 | pig faeces | AM889122 | 32 |
| tet(O/W)-2 | Megasphaera elsdenii 25-51 | swine faeces | AY485122 | 18,27 |
| tet(O/W)-1 [n = 15a] | M. elsdenii 27-51 | swine faeces | AY485126 | 27,33 |
| tet(O/W/O)-4 | uncultured bacterial clone | pig faeces | no accession number | 21 |
| tet(O/W/O)-3 [n = 9] | uncultured bacterial clone | pig faeces | EF065524 | 21 |
| tet(O/W/O)-2 [n = 28b] | M. elsdenii 14-14 | swine caecum | AY196920 | 13,18,27,33 |
| tet(O/W/O)-1 [n = 2] | M. elsdenii 7-11 | swine caecum | AY196921 | 13,18,27 |
| tet(O/W/32/O) [n = 32] | uncultured bacterial clone | pig faeces | EF065523 | 21 |
| tet(O/W/32/O) [n = 7c] | Streptococcus suis Ss1303 | pig (brain, lung and spleen) and human (CSF) samples | FM164392 | 34 |
| tet(O/W/32/O) | S. suis 32 457 | diseased pig lung | FR823304 | 34,35 |
| tet(O/W/32/O) | Streptococcus gallolyticus subsp. gallolyticus ATCC 2069 plasmid pSGG1 | human blood | FR824044 | 36 |
| tet(O/W/32/O) | S. suis | diseased pig (blood, brain, heart, joint and lung) samples | JQ740053 | 28 |
| tet(O/W/32/O/W/O) | Lactobacillus johnsonii G41 | human faeces | DQ525023 | 32 |
| tet(O/W/32/O/W/O) | uncultured bacterial clone | pig faeces | DQ679926 | 21 |
| tet(O/32/O) | S. suis | diseased pig (blood, brain, heart, joint and lung) samples | JQ740052 | 28 |
| tet(O/32/O) | Clostridium saccharolyticum K10 | human colon | AJ295238 | 18 |
| tet(O/32/O)-2 [n = 3] | uncultured bacterial clone | human and animal faecal samples | no accession number | 21 |
| tet(O/32/O)-3 | uncultured bacterial clone | human and animal faecal samples | no accession number | 21 |
| tet(O/32/O)-4 | uncultured bacterial clone | human and animal faecal samples | no accession number | 21 |
| tet(O/32/O)-5 | uncultured bacterial clone | human and animal faecal samples | no accession number | 21 |
| tet(O/32/O) | Dorea longicatena AGR2136 | rumen microbiome | NZ_AUJS01000017 (41 626–43 545 bp) | direct submission, analysed in this study |
| tet(O/32/O) | Campylobacter coli 202/04 | human faeces | AINH01000038 (2361–4280 bp) | direct submission, analysed in this study |
| tet(O/32/O) | C. coli 317/04 | human faeces | NZ_AINJ01000054 (2094–4013 bp) | direct submission, analysed in this study |
| tet(O/32/O) | Campylobacter jejuni subspecies jejuni 2008-894 | human | AIOQ01000025 (14 515–16 434 bp) | direct submission, analysed in this study |
| tet(O/32/O) | Roseburia intestinalis XB6B4 | human intestinal tract | FP929050 (2 873 814–2 875 733 bp) | direct submission, analysed in this study |
| tet(S/M) | Streptococcus equinus 1357 | food | HM367711 | 25 |
| tet(S/M) | Streptococcus intermedius | human isolate | AY534326 | 23,24 |
| tet(W/32/O) | B. thermophilum B0219 | environmental (pig slaughterhouse) sample | AM710601 | 32 |
| tet(W/32/O) | B. thermophilum B0241 | pig faeces | AM710602 | 32 |
| tet(W/32/O) | B. thermophilum B0242 | pig faeces | AM710603 | 32 |
| tet(W/32/O) | B. thermophilum B0253 | pig faeces | AM710604 | 32 |
| tet(W/32/O) | B. thermophilum B0256 | pig faeces | AM710605 | 32 |
The number given in square brackets indicates the instances of that mosaic gene variant reported, if more than one.
aFourteen of the 15 tet(O/W)-1 variants were only determined by PCR analysis and so could be either tet(O/W)-1 or tet(O/W)-2.
bEleven of the 28 tet(O/W/O)-2 variants were only determined by PCR analysis and so could be either tet(O/W/O)-2 or tet(O/W/O)-1.
cAll S. suis isolates, but not the same strain.