Table 2.

Clusters of Local Deformation in Subcortical Structures Correlated With Peak HIV RNA Load and With Nadir CD4%

Structure	Cluster no.	Direction of Deformation	No. of Vertices	Resolution Elementsa	Pb
Local deformation associated with peak HIV RNA load
Thalamus	1	Inward	500	6.11	.0078
	2	Inward	457	4.59	.0297
Caudate	1	Inward	578	10.87	.0006
	2	Inward	648	10.65	.0006
	3	Inward	550	7.72	.0048
	4	Outward	652	15.15	5.36 × 10–5
	5	Outward	526	13.34	.0001
	6	Outward	558	5.72	.0235
Globus pallidus	1	Inward	227	4.81	.0158
	2	Inward	239	3.67	.0478
Putamen	1	Inward	866	9.00	.0010
	2	Inward	656	5.80	.0122
	3	Inward	515	4.83	.0289
	4	Outward	274	6.60	.0062
Local deformation associated with nadir CD4%
Thalamus	1	Outward	780	10.41	.0003
	2	Outward	535	6.43	.006

Abbreviations: CD4%, CD4-positive T-lymphocyte percentage; HIV, human immunodeficiency virus.

^aResolution elements were defined by random field theory and estimate the spatial smoothness of the data and the number of independent statistical tests that should be performed.

^bAll P values (familywise error corrected) were <.05.