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. 2016 Nov 9;5(Suppl 1):S6–S14. doi: 10.1093/jpids/piw051

Table 2.

Clusters of Local Deformation in Subcortical Structures Correlated With Peak HIV RNA Load and With Nadir CD4%

Structure Cluster no. Direction of Deformation No. of Vertices Resolution Elementsa Pb
Local deformation associated with peak HIV RNA load
 Thalamus 1 Inward 500 6.11 .0078
2 Inward 457 4.59 .0297
 Caudate 1 Inward 578 10.87 .0006
2 Inward 648 10.65 .0006
3 Inward 550 7.72 .0048
4 Outward 652 15.15 5.36 × 10–5
5 Outward 526 13.34 .0001
6 Outward 558 5.72 .0235
 Globus pallidus 1 Inward 227 4.81 .0158
2 Inward 239 3.67 .0478
 Putamen 1 Inward 866 9.00 .0010
2 Inward 656 5.80 .0122
3 Inward 515 4.83 .0289
4 Outward 274 6.60 .0062
Local deformation associated with nadir CD4%
 Thalamus 1 Outward 780 10.41 .0003
2 Outward 535 6.43 .006

Abbreviations: CD4%, CD4-positive T-lymphocyte percentage; HIV, human immunodeficiency virus.

aResolution elements were defined by random field theory and estimate the spatial smoothness of the data and the number of independent statistical tests that should be performed.

bAll P values (familywise error corrected) were <.05.