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. 2016 Apr 7;25(12):2378–2392. doi: 10.1093/hmg/ddw105

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© The Author 2016. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Expression of FUS/caz variants has limited effect on motor behavior. Animals overexpressing wild-type or a pathogenic variant of FUS (A–C) or caz (D–F) in a wild-type background were assayed for (A and D) eclosion, (B and E) larval crawling, or (C and F) adult climbing ability, driven by D42-GAL4. N (animals) ≥ 100 (A, D), ≥20 (B, E), ≥50 (C, F). Control genotype is D42-GAL4/UAS-lacZ. Data in (C) and (F) are normalized to control. Statistical analysis was performed using one-way ANOVA with Sidak’s multiple comparison test, except (C) and (F) which were analyzed by Kruskal–Wallis non-parametric test with Dunn’s correction: *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Charts show mean ± SEM.