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. 2016 Apr 22;25(12):2404–2416. doi: 10.1093/hmg/ddw107

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© The Author 2016. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Opa3^L122P mice show site-specific dysregulation of marrow adiposity. Digital analysis of photomicrographs (inset; (adipocytes: black arrows); scale bar 20 µm (tibial images) 50 µm (vertebral images)) to quantify marrow adiposity, adipocyte number, adipocyte size and size distribution in tibiae (A) and L3 vertebrae (B) from 30-day-old male WT (n = 6 (tibiae) and 5 (vertebrae)) and homozygous Opa3^L122P littermate mice (n = 6 (tibiae) and 3 (vertebrae)). Data presented are mean ± SEM, with statistical analysis performed by unpaired Student’s t test; a P < 0.05 versus WT males.