Table 1.
Skull morphometry in 14-day-old WT and Opa3L122P littermates
| WT (n=9) | Opa3L122P(n=5) | |
|---|---|---|
| Skull Length (mm) | 17.43 ± 0.21 | 15.76 ± 0.29 *** |
| External cranial volume (mm3) | 1892.37 ± 93.82 | 1644.25 ±104.83 |
| Cranial dome angle (°) | 25.1 ± 1.5 | 23.9 ± 1.9 |
| Nasal height (mm) | 3.88 ± 0.06 | 3.56 ± 0.12 * |
| Nasal length (mm) | 4.69 ± 0.14 | 4.54 ± 0.25 |
| Mandibular height (mm) | 3.38 ± 0.08 | 3.00 ± 0.06 ** |
| Mandibular length (mm) | 6.06 ± 0.09 | 5.23 ± 0.11 *** |
| Upper incisor length (mm) | 1.67 ± 0.10 | 1.45 ± 0.04 |
| Lower incisor length (mm) | 2.36 ± 0.08 | 2.04 ± 0.09 * |
| Incisor misalignment (mm) | 0.03 ± 0.01 | 0.16 ± 0.06 * |
Values shown are mean ± SEM (n = 9 (WT; 4 males/5 females) and 5 (Opa3L122P; 3 males/2 females)), with statistical comparisons performed with unpaired Student’s t-test.
*
P < 0.05.
**
P < 0.01.
***
P < 0.001.