Table 1.

Summary of GWAS meta-analysis results for loci with P < 5 × 10⁻⁷

GWAS analysis population	Locus	SNP	Risk allele	TDT OR	CC OR	Meta OR	95% CI	P-value
Multi-ethnic	1p36.13	rs4920524	G	1.33	1.34	1.34	1.21-1.47	3.72E−09
	1p22.1	rs4147882	T	1.49	1.33	1.42	1.28-1.58	5.59E−11
	1q32	rs11119345	G	1.78	1.85	1.81	1.57-2.07	2.52E−17
	2p22	rs372148350	AT	1.37	1.80	1.49	1.28-1.74	2.50E−07
	2p24.2	rs7552	G	1.36	1.18	1.28	1.17-1.40	4.22E−08
	5p12	rs59569344	G	1.31	1.39	1.34	1.19-1.50	4.75E−07
	5q13.1	rs831227	T	1.24	1.26	1.25	1.15-1.36	5.34E−07
	8q21.3	rs12543318	C	1.31	1.16	1.25	1.15-1.36	2.11E−07
	8q22.2	rs1788160	G	1.35	1.20	1.29	1.17-1.41	9.52E−08
	8q24	rs55658222	A	2.08	1.91	2.00	1.78-2.26	5.63E−30
	9q21.31	rs6559624	T	1.45	1.19	1.34	1.20-1.50	1.72E−07
	10q26.3	rs7922405	A	1.24	1.25	1.25	1.14-1.36	4.60E−07
	15q24	rs28689146	A	1.24	1.35	1.28	1.17-1.40	5.40E−08
	17p13.1	rs11273201	AACCCAAAACCCAC	1.44	1.43	1.44	1.29-1.59	7.84E−12
	19q13.11	rs73039428	A	1.65	1.31	1.50	1.30-1.73	2.92E−08
European	1p36.13	rs9439714	C	1.62	1.38	1.52	1.30-1.89	1.91E−07
	6p21.33	rs79411602	C	1.67	1.31	1.52	1.29-1.78	2.92E−07
	8q24	rs72728734	G	2.22	1.84	2.04	1.70-2.44	7.33E−15
	17p13.1	rs7406226	A	1.50	1.73	1.59	1.33-1.89	2.16E−07
	17q23.2	rs1588366	A	1.63	2.09	1.78	1.46-2.17	1.41E−08
Asian	1q32	rs1044516	G	1.63	2.04	1.71	1.38-2.11	1.01E−06
	17p13.1	rs11078735	C	2.62	1.52	2.27	1.65-3.12	4.20E−07
Central/ South American	1p22.1	rs4147882	T	1.55	1.41	1.48	1.27-1.73	3.99E−07
	1p32	rs11119345	G	1.85	1.77	1.81	1.55-2.13	3.40E−13
	2q21	rs4850293	G	2.56	3.55	2.94	1.95-4.44	2.87E−07
	6p12.3	rs6918746	A	1.27	1.59	1.40	1.23-1.59	1.65E−07
	8p23.1	rs10780175	T	1.38	1.41	1.39	1.22-1.59	4.90E−07
	8q24	rs55658222	A	1.92	1.92	1.92	1.62-2.27	3.98E−14
	16p13	rs111698437	T	2.33	3.39	2.74	1.86-4.03	3.67E−07
	17p13.1	rs7406226	A	1.60	1.28	1.45	1.28-1.65	1.46E−08
	17q22	rs227727	T	1.41	1.37	1.39	1.22-1.58	5.73E−07
	21q22	rs4920143	T	1.52	1.38	1.46	1.26-1.68	2.04E−07