Table 1.
Physiological parameters during MRS scanning
| Breathing Rate | Body Temperature | Isoflurane Level | ||||
|---|---|---|---|---|---|---|
| wild type | R6/2 | wild type | R6/2 | wild type | R6/2 | |
| Experiment | mean (sd) | mean (sd) | mean (sd) | mean (sd) | mean (sd) | mean (sd) |
| Basal | 109.8 (11.8) | 120.3 (12.5) | 37.9 (0.3) | 36.9 (0.4)** | 1.4 (0.1) | 1.5 (0.2) |
| After saline | 104.0 (20.6) | 119.0 (13.2) | 37.9 (0.2) | 37.4 (0.3)*ˆ | 1.3 (0.3) | 1.4 (0.1) |
| N | 5 | 3 | 5 | 3 | 5 | 3 |
| Basal | 104.1 (16.4) | 121.6 (14.8)* | 37.6 (1.1) | 37.5 (0.5) | 1.3 (0.2) | 1.2 (0.4) |
| After DNP | 105.0 (16.7) | 108.6 (19.9) | 37.9 (0.9) | 37.8 (0.5) | 1.2 (0.3) | 1.2 (0.3) |
| N | 10 | 11 | 10 | 11 | 10 | 11 |
| Basal | 107.9 (10.3) | 120.6 (23.3) | 37.6 (0.5) | 38.2 (0.6)* | 1.1 (0.3) | 1.1 (0.3) |
| After oligo | 108.3 (19.8) | 111.5 (23.1) | 37.8 (0.4)ˆˆˆ | 38.1 (0.4) | 1.1 (0.3) | 1.0 (0.2) |
| N | 10 | 11 | 10 | 11 | 10 | 11 |
*, **
p < 0.05, p < 0.01 compared to wild type, unpaired t test.
ˆ, ˆˆˆ
p < 0.05, p = 0.001 compared to basal condition, paired t test.