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. 2016 Dec 15;5(4):343–346. doi: 10.3233/JHD-160217

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Fig.2 — S830 staining of 7 week-old heterozygous (A, B) and homozygous (C, D) zQ175 mouse brain. In heterozygous Q175 mice, A and B, minimal neuronal nuclear cellular staining was limited to the CA1 region, the parasubiculum (PaS) and deep layer V neurons in entorhinal cortex (Ent, TeA), while diffuse staining (reduced or absent at later ages) was present in these regions and in the substantia nigra (SNR). At 7 weeks of age homozygous zQ175 mouse brain, C and D, showed exclusively neuronal nuclear staining, in CA1 region of dentate gyrus (DG), in parasubiculum (PaS), and in cortex, with primary visual (V1), somatosensory (S1), temporal association (TeA), retrosplenial (RS) and entorhinal (Ent) shown here.