Table 2.

Patients with neoadjuvant chemotherapy. N.a. = not available due to lack of tumor tissue in a pT0, pN0 situation. LA = locally advanced in CT staging. LN+ = suspicious lymph nodes in preoperative staging. * = Urothelial carcinoma of the upper urinary tract

Preoperative		Postoperative		Response	Histology	Indication
PD-L1-Tumor	CD8	PD-L1-Tumor	CD8
negative	high	n.a.	n.a.	yes	pT0, pN0	LA
negative	low	n.a.	n.a.	yes	pTis, pN0	LN+/LA
negative	high	n.a.	n.a.	yes	pTa, pN0	LN+
negative	high	n.a.	n.a.	yes	pT0, pN0*	LN+/LA
negative	low	n.a.	n.a.	yes	pT0, pN0	LN+/LA
positive	high	negative	high	yes	pT1, pN0	LA
positive	high	n.a.	n.a.	yes	pT0, pN0	LN+
positive	high	n.a.	n.a.	yes	pT0, pN0	LA
negative	high	negative	high	no	pT2b, pN0	LA
negative	low	negative	low	no	pT3a, pN0	LA
negative	low	negative	low	no	pT3b, pN3	LA
negative	low	negative	low	no	pT0, pN1	LA
negative	low	negative	high	no	pT3a, pN0	LA
negative	low	negative	low	no	pT4b, pN1	LA
negative	high	negative	high	no	pT3b, pN1	LA
negative	high	negative	low	no	pT3a, pN3	LN+
negative	low	negative	low	no	pT4a, pN3	LN+/LA
positive	high	positive	high	no	pT4a, pN3	LN+/LA
positive	low	x	x	no	pT3b, pN0	LN+/LA
positive	high	positive	low	no	pT3b, pN3	LN+/LA
positive	high	positive	high	no	pT3, pN1*	LN+/LA
positive	high	positive	high	no	pT3b, pN2	LN+/LA