TABLE 2 .
Amino acid differences in S-CDT subunits between serotype Typhi and nontyphoidal serotypes
| S-CDT subunit | Amino acid residue | Amino acid (nucleotide codon) ina: |
Serotype(s) with substitution | |
|---|---|---|---|---|
| CT-18 | Serotype(s) | |||
| CdtB | 217 | Ala (GCC) | Thr (ACC) | Mississippi |
| 223 | Glu (GAA) | Ala (GCA) | Mississippi | |
| PltBb | 3 | Met (ATG) | Ile (ATA) | Javiana, Montevideo, Mississippi, Oranienburg |
| 4 | Ser (AGT) | Asn (AAT) | Javiana, Montevideo, Mississippi, Oranienburg | |
| 6 | Tyr (TAT) | Phe (TTT) | Javiana, Montevideo, Mississippi, Oranienburg | |
| 29 | Asn (AAT) | Lys (AAA) | Javiana, Montevideo, Oranienburg | |
| 50 | Ser (AGT) | Gly (GGT) | Javiana, Oranienburg | |
| 65 | Thr (ACA) | Ile (ATA) | Javiana, Oranienburg (1 of the 5 isolates) | |
| 116 | Thr (ACC) | Ala (GCC) | Oranienburg (4 of the 5 isolates) | |
| PltAc | 6 | Phe (TTC) | Leu (CTC) | Javiana, Oranienburg |
| 169 | Ala (GCC) | Ser (TCC) | Javiana, Montevideo, Oranienburg | |
| 215 | His (CAT) | Gln (CAA) | Javiana, Montevideo, Mississippi, Oranienburg | |
| 227 | Met (ATG) | Val (GTG) | Javiana | |
a
The three-letter abbreviations for the amino acid residues in S. enterica serotype Typhi strain CT-18 or in the nontyphoidal serotypes are shown; codons encoding the amino acid residues are shown in parentheses. The specific SNPs causing the amino acid change are shown in bold font.
b
Salmonella Oranienburg strain FSL A4-0642 showed the same amino acid substitution in PltB as the 5 Javiana isolates tested.
c
In addition to having the amino acid differences listed here, isolate FSL R8-1549 (serotype Mississippi) had an SNP resulting in an amino acid change from glycine to serine at position 211; this genotype was not detected in any other isolates.