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. 2016 Nov 23;50(1):31–40. doi: 10.3892/ijo.2016.3778

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Copyright: © Chen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Expression of STMN1 and Ki-67 in HSCC or normal tissues. (A) STMN1 versus Ki-67 was differentially expressed between HSCC and normal tissues as proved by immunohistochemical staining. (a and b) Negative STMN1; (c and d) weak STMN1; (e and f) negative Ki-67; (g and h) weak Ki-67; (i and j) moderate STMN1; (k and l) strong STMN1; (m and n) moderate Ki-67; (o and p) strong Ki-67 expression in normal tissue (NT), cancer in situ (CIS), early invasive tumor and advanced tumor, respectively (magnification, ×100 and ×400). (B) Scatterplot of Ki-67 versus STMN1 with regression line showed a correlation using the Spearman's correlation coefficient (R²=0.74, P=0.000). (C and D) Distribution of STMN1 IHC score in samples. ^*P<0.05, ^**P<0.01, statistically significant. Data were expressed as the mean ± SD.