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. 2016 Dec 19;12:13–25. doi: 10.2147/COPD.S114209

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© 2017 Calverley et al. This work is published and licensed by Dove Medical Press Limited

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CONSORT patient flow through the three studies and analyses performed.

Notes: ^aOther patients in the study were randomized to other treatment groups that are not represented in this figure. Reprinted with permission of the American Thoracic Society. Copyright © 2016 American Thoracic Society. Welte T, Miravitlles M, Hernandez P, et al. Efficacy and tolerability of budesonide/formoterol added to tiotropium in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2009;180(8):741–750.¹⁰ The American Journal of Respiratory and Critical Care Medicine is an official journal of the American Thoracic Society.

Abbreviations: AE, adverse event; B/F, budesonide/formoterol; COPD, chronic obstructive pulmonary disease; EAS, efficacy analysis set for pooled analysis; FAS, full analysis set for pooled analysis; PBO, placebo; PN, predicted normal.