Table 2. Statistics of the commonly and oppositely regulated gene expression and pathway activation markers in the pediatric and in the adult AML.

Matches	Gene expression markers	Pathway activation markers
Complete matches - concordant	(7) CAMK2B, EIF4B, HAPLN1, HIST1H3B, LIPE, MAPK13, SAR1B	(2) CD40 pathway (cell survival), Ras pathway (CDC42 signaling)
Complete matches - discordant	(4) BID, F2, JAK3, PPARA	(1) ATM Pathway (Cell Cycle Checkpoint Control)
Incomplete matches – concordant	Not applicable	(14) EGF Pathway (Cell Survival), EGF Pathway (IP3 Signaling), EGF Pathway (Rab5 Regulation Pathway), Glucocorticoid Receptor Pathway (Cell Cycle Progression), Glucocorticoid Receptor Signaling Pathway (Gene Expression via CREB3, STAT5B, SLC22A2, POU2F1), JAK-STAT Pathway, JAK-STAT Pathway (Nml, SOCS, BCL-XL p21, Myc, Nos2, Gene Expression via STAT2), JAK-STAT Pathway (Gene Expression via MYC), Mitochondrial Apoptosis Pathway (DNA Fragmentation), Mitochondrial Apoptosis Pathway (Apoptosis), Ras Pathway (Receptor Endocytosis), Ras Pathway (Increased T-cell Adhesion), TGF-Beta Pathway, TGF-Beta Pathway (Transciption, Arrested Growth, Apoptosis)
Incomplete matches - discordant	Not applicable	(17) ATM Pathway, ATM Pathway (S-phase progression), ATM Pathway (Apoptosis), ATM Pathway (Apoptosis and Senescence), ATM Pathway (Checkpoint Activation), ATM Pathway (G2-Mitosis progression), ILK Pathway (Cell Adhesion), ILK Pathway (Opsonization), ILK Pathway (Cell Cycle, Proliferation), ILK Pathway (Cell Migration, Retraction), Mitochondrial Apoptosis Pathway (Gene Expression via TP53), NGF Pathway (Actin Polymerization, Neurite Outgrowth and Differentiation), NGF Pathway (Neurite Outgrowth and Differentiation), PPAR Pathway, PPAR Pathway (Adipocyte Differentiation, Glucose Homeostasis and Macrophage Function), VEGF Pathway, VEGF Pathway (Actin Reorganization).