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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Osteoarthritis Cartilage. 2016 Aug 25;25(1):108–117. doi: 10.1016/j.joca.2016.08.008

Fig. 6.

Fig. 6

Osteoarthritic changes in meniscus, synovium and subchondral trabecular bone at 8 weeks after DMM surgery. a) Meniscus: AFM-based nanoindentation on meniscus surfaces illustrated marked modulus reduction on the medial side, and marginal changes on the lateral side after DMM (n = 5, each error bar represents 95% CI). b) Synovium: hematoxylin and eosin (H&E) staining showed no appreciable morphological differences (n = 4). c) Subchondral trabecular bone, left panel: frontal plane of μCT images, right panel: trabecular structural parameters calculated from μCT images (n = 10). Neither panel exhibited significant differences between DMM versus Sham knees.