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. Author manuscript; available in PMC: 2018 Jan 10.
Published in final edited form as: Int J Pharm. 2016 Oct 31;516(1-2):196–203. doi: 10.1016/j.ijpharm.2016.10.072

Figure 4.

Figure 4

Skin distribution of Vitamin D3 loaded in TyroSphere (VD3-Tyr) at 4 and 15 wt% initial loading and VD3 dissolved in Transcutol® (containing about 0.8, 1.5 and 1.5 mg/mL VD3 in the formulation). The bars show drug extracted from epidermis and dermis (μg per cm2 area of skin) following 3, 5 and 12 h of skin exposure to the formulation. The statistical data is expressed as mean ± SEM (n = 5), * P<0.05, ** P<0.01.