Table 2.
Canonical Pathways from Biological Pathway Analyses.
| Surgery-Responsive (ANCOVA) |
Correlated to HOMA |
|||||||
|---|---|---|---|---|---|---|---|---|
| Ingenuity Canonical Pathway |
−log (p- value) |
Ratio | Genes in Dataset |
Total Genes in Pathway |
−log(p- value) |
Ratio | Genes in Dataset |
Total Genes in Pathway |
| B Cell Receptor Signaling |
5.50 | 0.27 | 47 | 176 | 4.78 | 0.36 | 64 | 176 |
| ERK/MAPK Signaling |
4.22 | 0.24 | 46 | 190 | 7.86 | 0.41 | 77 | 190 |
| IGF-1 Signaling | 4.00 | 0.28 | 28 | 99 | 5.19 | 0.42 | 42 | 99 |
| Wnt/Beta-catenin Signaling |
3.97 | 0.25 | 41 | 167 | 4.35 | 0.36 | 60 | 167 |
| AMPK Signaling | 3.88 | 0.25 | 37 | 194 | 4.16 | 0.35 | 67 | 194 |
| Apoptosis Signaling* |
3.67 | 0.28 | 25 | 88 | NS* | |||
| SAPK/JNK Signaling |
3.59 | 0.28 | 26 | 94 | 5.01 | 0.43 | 40 | 94 |
| FGF Signaling | 3.58 | 0.28 | 25 | 89 | 2.93 | 0.37 | 33 | 89 |
| HGF Signaling | 3.38 | 0.26 | 28 | 107 | 9.21 | 0.50 | 53 | 107 |
| Cardiac Hypertrophy Signaling |
3.35 | 0.22 | 50 | 229 | 5.63 | 0.36 | 82 | 229 |
| 14-3-3-mediated Signaling |
3.34 | 0.25 | 30 | 118 | 2.85 | 0.35 | 41 | 118 |
| Tight Junction Signaling |
3.09 | 0.23 | 38 | 166 | 3.84 | 0.35 | 58 | 166 |
| Corticotropin Releasing Hormone Signaling |
3.06 | 0.25 | 29 | 117 | 2.93 | 0.35 | 41 | 117 |
| p38 MAPK Signaling |
3.06 | 0.25 | 29 | 117 | 4.22 | 0.39 | 45 | 117 |
| Insulin Receptor Signaling |
3.02 | 0.24 | 32 | 134 | 4.90 | 0.39 | 52 | 134 |