Table 2.

Lesion volume at baseline and last time point for all 22 participants.

Lesion #	Age at baseline (years)	Sex	Disease stage at baseline	Disease stage at follow up	Unadjusted LV at baseline (μL)	Unadjusted LV at last time point (μL)	No of scans available	Duration of follow up	% change from mixed-effects model	Slope from mixed-effects model
1	34	M	RRMS	RRMS	156.7	81.6	8	17.4	−4.33	−0.044
2	31	M		SPMS	145.7	35	15	19.3	−7.59	−0.079
3	30	M	RRMS	SPMS	153.3	87.3	13	21.5	−2.00	−0.020
4	36	F	RRMS	SPMS	83.4	6	13	15.8	−9.23	−0.097
5	26	F	RRMS	SPMS	144.4	55.6	2	16.7	−5.80	−0.060
6	20	M	RRMS	SPMS	190	133.6	11	14.8	−4.66	−0.048
7	28	M	RRMS	RRMS	129.5	68.9	19	19.4	−2.49	−0.025
8	29	F	RRMS	RRMS	54	20.6	14	13.8	−4.57	−0.047
9	31	M	RRMS	RRMS	151.6	53	15	14.1	−5.38	−0.055
10	34	F	RRMS	RRMS	368	171	15	15.9	−2.56	−0.026
11	38	F	RRMS	SPMS	40.2	69.8	14	19.0	−1.65	−0.017
12	49	F	RRMS	RRMS	56.9	12.8	13	19.5	−6.67	−0.069
13	14	F	RRMS	SPMS	172.8	139.1	18	17.7	−2.35	−0.024
14	39	M	RRMS	RRMS	291.8	204	15	18.9	−1.77	−0.018
15	35	F		SPMS	211.1	54	13	15.8	−10.30	−0.109
16	25	F	RRMS	RRMS	85.3	39.6	17	17.3	−4.12	−0.042
17	37	F	RRMS	SPMS	92	102.5	16	16.9	−2.27	−0.023
18	23	M	RRMS	RRMS	221.3	102	3	16.5	−4.51	−0.046
19	47	F	RRMS	SPMS	132.9	42.5	13	15.7	−4.66	−0.048
20	27	F	RRMS	RRMS	59.3	52.4	3	5.8	−3.81	−0.039
21	43	F	RRMS	RRMS	144.9	66.4	13	14.7	−5.02	−0.052
22	17	F	RRMS	RRMS	34.6	35.4	3	13.4	−3.14	−0.032
Mean	32				141.8	74.2	Median 13	16.4	−4.5	−0.046
Standard deviation	9				82.1	50.7	Range 2 to 19	3.2	2.3	0.025

Abbreviations. LV: lesion volume; RRMS: relapsing-remitting multiple sclerosis; SPMS: secondary porgressive multiple sclerosis.