Table 3.

Nuclear receptor signalling pathway components across unikonts. IC, intracellular.

^aSee glossary for gene and species abbreviations.

*Homologues identified by reciprocal BLAST against the Amphimedon queenslandica NR database; accession numbers available in electronic supplementary material. White boxes—no homologue reported in the literature or detected by BLAST. Grey boxes—putative/degenerate homologue. Black boxes—homologue present. The origin of the canonical/functional NR pathway is considered to be coincident with the origin of metazoan NR homologs and is indicated by the bold line.