Table 5.

Hedgehog signalling pathway components across unikonts. EC, extracellular; IC, intracellular; MB, membrane bound.

^aSee glossary for gene and species abbreviations.

*Homologues identified by reciprocal BLAST against the human NR database; accession numbers available in electronic supplementary material. White boxes—no homologue reported in the literature or detected by BLAST. Grey boxes—putative/degenerate homologue. Black boxes—homologue present. The origin of the canonical/functional pathway is indicated by the bold line.