Fig. 5.

Changes in serum BK and DABK during the consolidation phase of TB therapy. DABK decreases and modest BK changes were observed versus induction phase values in most patients (a, b, d, e), although two patients lacked induction phase data, preventing this comparison (c, f) and one patient had reduced DABK and rising BK levels after their discharge date (e). One patient with second episode of TB disease showed both elevated DABK and BK after their treatment discharge date, suggesting treatment failure, corresponding to a suspected third episode of recurrent TB disease (g). Red line: positive sputum culture; Green line: negative sputum culture; Black line: end of treatment; All EPTB patients had an initial positive Mtb culture from a biopsy specimen. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)