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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Pediatr. 2016 Oct 13;180:170–176. doi: 10.1016/j.jpeds.2016.09.003

Figure 2.

Figure 2

Differences in brain water content measurements during DKA compared with post-recovery (n=10), expressed as percent changes. The line in the middle of each box indicates the median (50% percentile), the top and bottom indicate the 75th / 25th percentiles, the diamond indicates the mean. The whiskers extend toward the maximum and minimum values to a maximum length of 1.5 interquartile ranges. Individual values beyond the whiskers are possible outliers. For imputed values, the depicted value is based on the geometric mean treatment to recovery ratio across the 100 multiple imputation datasets.

Region-specific geometric mean (95% CI) treatment to recovery ratios (GMR) and between-region ratio of geometric mean ratios
GMR (95% CI) RGMR (95% CI), Relative to Occipital Cortex
Frontal cortex 1.03 (0.999, 1.07) 1.05 (0.99, 1.12)
Basal ganglia 1.05 (0.99, 1.11) 1.06 (0.99, 1.14)
Hippocampus 1.09 (0.90, 1.32) 1.11 (0.92, 1.34)
Thalamus 1.04 (0.98, 1.10) 1.06 (0.98, 1.14)
Occipital cortex 0.98 (0.92, 1.05) Reference

Pooled estimates from 100 multiple imputation datasets.