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. Author manuscript; available in PMC: 2018 Feb 15.
Published in final edited form as: Behav Brain Res. 2016 Nov 11;319:31–36. doi: 10.1016/j.bbr.2016.11.016

Figure 2.

Figure 2

The Ywhae deficiency resulted in hyperactivity. Open field test revealed increased locomotor activity in the Ywhae heterozygous and homozygous knockout mice. Total travel distance (A) and vertical activity (B) were calculated. (C) Increased time spent in the center area in the homozygous Ywhae knockout mice (KO/KO). (D) Ethological assessment of spontaneous behaviors shows an increase in locomotion and a decrease in total rearing and realing free in Ywhae deficient mice. Significance was analyzed by one-way ANOVA with Bonferroni’s post-hoc test. * p<0.05, ** P<0.01 and *** P<0.001.