Fig. 2. Sarcomere number adaptation occurs after satellite-cell reduction.
Serial sarcomere number addition in soleus (A) and subtraction in tibialis anterior (B) muscles from casted and uncasted hindlimbs of wild-type, tamoxifen-treated mice (tamoxifen control group); Pax7-DTA, tamoxifen-treated mice (experimental group); and Pax7-DTA, vehicle-treated mice (treatment control group). Data are plotted as mean + SEM (N=10 for experimental group, N=7–8 for control groups).* Statistically significant difference between casted and uncasted hindlimbs (P<0.05).