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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Muscle Nerve. 2016 Nov 28;55(3):384–392. doi: 10.1002/mus.25227

Fig. 3. Satellite cell depleted muscle is fibrotic with decreased muscle fiber sizes.

Fig. 3

(A) H&E stains of vehicle-treated Pax7-DTA soleus (left) and tamoxifen-treated Pax7-DTA soleus (right) on the cast side with a 20X objective (Scale bar = 50 μm). Images are representative of results from 5 independent samples per group. (B) Laminin antibody labeling of vehicle-treated Pax7-DTA soleus (left) and tamoxifen-treated Pax7-DTA soleus (right) on the cast side using a 10X objective (Scale bar = 100 μm, for all images). Displayed images are representative of 4–5 independent samples per group. (C) Quantification of percentage area of H&E stained sections of the soleus that was muscle tissue. (D) Quantification of soleus myofiber area calculated from laminin-labeled samples (n=4–5 per group). Data are represented as mean ± SEM. *statistically significant differences compared to uncasted sided and vehicle-treatment, P<0.05 (D) and **P<0.01 (C).

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