Table 3.

Quantitative evaluation of the quality of fit between warped template label maps and blocky ASHS label maps in subject space. Average Dice similarity coefficient (top) and average Hausdorff distance (bottom) are reported (standard deviation in parentheses).

Approaches	Labels that are highly variable			Relatively consistent labels
	BA35	BA36	CSPRC	ERC	PHC	CSPHC
Average Dice Similarity Coefficient
Left Hemisphere
Single Template	0.952 (± 0.015)	0.957 (± 0.013)	0.799 (± 0.075)	0.982 (± 0.005)	0.977 (± 0.008)	0.927 (± 0.031)
Variant Template	0.960 (± 0.015)**	0.972 (± 0.011)**	0.865 (± 0.091)**	0.981 (± 0.005)**	0.978 (± 0.009)**	0.935 (± 0.029)**
Unified Template	0.948 (± 0.015)**	0.967 (± 0.011)**	0.856 (± 0.069)**	0.976 (± 0.005)**	0.972 (± 0.010)**	0.948 (± 0.025)**
Right Hemisphere
Single Template	0.952 (± 0.011)	0.971 (± 0.011)	0.774 (± 0.098)	0.981 (± 0.006)	0.981 (± 0.008)	0.946 (± 0.031)
Variant Template	0.961 (± 0.011)**	0.976 (± 0.008)**	0.850 (± 0.074)**	0.981 (± 0.007)*	0.981 (± 0.008)	0.947 (± 0.032)
Unified Template	0.958 (± 0.011)**	0.978 (± 0.008)**	0.825 (± 0.093)**	0.984 (± 0.005)**	0.983 (± 0.007)**	0.954 (± 0.027)**
Average Hausdorff Distance (mm)
Left Hemisphere
Single Template	0.117 (± 0.035)	0.180 (± 0.047)	0.637 (± 1.060)	0.066 (± 0.020)	0.084 (± 0.022)	0.202 (± 0.237)
Variant Template	0.104 (± 0.046)**	0.119 (± 0.050)**	0.431 (± 0.864)**	0.070 (± 0.028)**	0.080 (± 0.021)**	0.177 (± 0.201)**
Unified Template	0.126 (± 0.029)**	0.134 (± 0.043)*	0.467 (± 0.907)**	0.081 (± 0.015)**	0.100 (± 0.017)**	0.163 (± 0.185)**
Right Hemisphere
Single Template	0.113 (± 0.028)	0.122 (± 0.065)	0.492 (± 0.686)	0.067 (± 0.017)	0.081 (± 0.045)	0.127 (± 0.141)
Variant Template	0.096 (± 0.021)**	0.101 (± 0.051)**	0.311 (± 0.466)**	0.066 (± 0.008)	0.077(± 0.033)**	0.121 (± 0.112)
Unified Template	0.114 (± 0.028)	0.103 (± 0.039)**	0.372 (± 0.544)**	0.067 (± 0.016)	0.082 (± 0.041)	0.120 (± 0.106)

Note:

^*p < 0.05;

^**p < 0.01. Compared with single-template approach, tested by two-tailed paired t-tests.