Figure 1.

Relative Risk (RR) of Fatal Coronary Heart Disease (CHD) per 1-SD Increase in the Biomarkers α-Linolenic Acid (ALA; 18:3ω-3) and Eicosapentaenoic Acid (EPA; 20:5ω-3)

Estimates were pooled using random effects meta-analysis. See eFigure 1 in the Supplement for results using inverse-variance weights. CHS indicates Cardiovascular Health Study²⁰; EPIC-Norfolk, European Prospective Investigation of Cancer (Norfolk)²¹; HPFS, Health Professionals Follow-up Study²³; KIHD, Kuopio Ischaemic Heart Disease Risk Factor Study²⁵; MCCS, Melbourne Collaborative Cohort Study²⁶; MESA, Multi-Ethnic Study of Atherosclerosis²⁷; NHS, Nurses’ Health Study³⁰; NSHDS, Northern Sweden Health and Disease Study^28,29; PHS, Physician’s Health Study³¹; SCHS, Singapore Chinese Health Study³³; and ULSAM, Uppsala Longitudinal Study of Adult Men.³⁵