Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cumulative dose response curves of POLE wild type vs POLE-mutated EC cell lines after exposure to Carboplatin (upper panel) and Paclitaxel (lower panel). POLE mutated cell lines are significantly more resistant than POLE wild-type cell lines to Carboplatin (P =0.004), but not to Paclitaxel (P =0.140).
