Table 2. Experiment 2.
Effects of chronic (5 day) administration of vehicle (V) and doses of 3-ISOPBC on seeking in Component 2 (C2) for alcohol (Alcohol Group) and a non-alcoholic beverage (Control Group) under the chained schedule of reinforcement. Baseline (BL) is the grand mean of the 3 days preceding each chronic condition.
Alcohol Group | BL | V | 3-ISOPBC dose (mg/kg) | F(4,16) | ||||
---|---|---|---|---|---|---|---|---|
| ||||||||
5.0 | 10.0 | 20.0 | ||||||
C2 | Left Lever FI Resp | Mean | 141. 2 | 394.5 | 212.3 | 161.5 | 198.2 | 1.93 |
SEM | 68.4 | 217.4 | 118.1 | 107.4 | 113.1 | |||
| ||||||||
Left Lever FI Resp Latency (s) | Mean | 639. 5 | 620.4 | 706.0 | 676.5 | 755.3 | 1.05 | |
SEM | 20.2 | 10.8 | 58.1 | 52.0 | 93.2 | |||
| ||||||||
Control Group | BL | V | 5.0 | 10.0 | 20.0 | F(4,8) | ||
| ||||||||
C2 | Left Lever FI Resp | Mean | 144. 9 | 128.2 | 200.4 | 154.8 | 75.0 | 1.03 |
SEM | 96.2 | 55.3 | 131.1 | 85.1 | 37.7 | |||
| ||||||||
Left Lever FI Resp Latency (s) | Mean | 609. 7 | 674.6 | 612.8 | 624.7 | 735.0 | 1.33 | |
SEM | 5.3 | 20.7 | 11.3 | 18.3 | 95.1 |
Note: FI, Fixed Interval; FR, Fixed Ratio; Resp, Response; Alc, Alcohol.