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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Drug Alcohol Depend. 2016 Nov 4;170:25–31. doi: 10.1016/j.drugalcdep.2016.10.036

Table 2. Experiment 2.

Effects of chronic (5 day) administration of vehicle (V) and doses of 3-ISOPBC on seeking in Component 2 (C2) for alcohol (Alcohol Group) and a non-alcoholic beverage (Control Group) under the chained schedule of reinforcement. Baseline (BL) is the grand mean of the 3 days preceding each chronic condition.

Alcohol Group BL V 3-ISOPBC dose (mg/kg) F(4,16)

5.0 10.0 20.0
C2 Left Lever FI Resp Mean 141. 2 394.5 212.3 161.5 198.2 1.93
SEM 68.4 217.4 118.1 107.4 113.1

Left Lever FI Resp Latency (s) Mean 639. 5 620.4 706.0 676.5 755.3 1.05
SEM 20.2 10.8 58.1 52.0 93.2

Control Group BL V 5.0 10.0 20.0 F(4,8)

C2 Left Lever FI Resp Mean 144. 9 128.2 200.4 154.8 75.0 1.03
SEM 96.2 55.3 131.1 85.1 37.7

Left Lever FI Resp Latency (s) Mean 609. 7 674.6 612.8 624.7 735.0 1.33
SEM 5.3 20.7 11.3 18.3 95.1

Note: FI, Fixed Interval; FR, Fixed Ratio; Resp, Response; Alc, Alcohol.

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