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Receptor / β-arrestin 2 interaction studies. Concentration response curves to N/OFQ, dermorphin, [Dmt1]N/OFQ(1-13)-NH2 and PWT2-[Dmt1] in CHO cells stably expressing the NOP/RLuc (panel A) or mu/RLuc (panel B) and the β-arrestin 2/RGFP protein. Data are expressed as the mean ± S.E.M. for at least 4 separate experiments performed in duplicate.
