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. Author manuscript; available in PMC: 2018 Jan 5.
Published in final edited form as: Eur J Pharmacol. 2016 Nov 19;794:115–126. doi: 10.1016/j.ejphar.2016.11.026

Table 1.

Displacement binding experiments. pKi (CL95%) values of [Dmt1]N/OFQ(1-13)-NH2 and PWT2-[Dmt1] in CHO cells expressing recombinant human NOP and classical opioid receptors.

NOP mu kappa delta
[Dmt1]N/OFQ(1-13)-
NH2 		10.39
(9.31-10.48)		 10.04
(9.43-10.65)		 10.38
(10.31-10.44)		 9.99
(9.82-10.16)
PWT2-[Dmt1] 9.13
(7.80-10.45)		 9.25
(8.73-9.77)		 9.13
(9.02-9.25)		 8.42
(8.22-8.62)

N/OFQ, dermorphin, dynorphin A and DPDPE were used as standard ligands for the NOP, mu, kappa and delta receptors respectively.