Table 1.
Comparison of the four fitting approaches based on the 2-pool model, progressively fixing more parameters. Averages (Av) and SD (n=11) are shown for f and kMW for the SCC ROI, together with fit residue. The SD of the differences the 3 and 7 T data (diff) is an indication of the intra-subject reproducibility, the residue is reflects the fitting of the 2-pool model, which is the same for approaches 1 and 2 (both contain only 2 assumptions and therefore the same free fit of Eq. 1 to the data).
| Approach 1: Fixed R1,MP, R1,WP |
Approach 2: Fixed R1,MP, FSMP(0) |
Approach 3: + fixed R1,WP |
Approach 4: + fixed FSWP(0) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Av | SD | Av | SD | Av | SD | Av | SD | ||
| f | 3 T | 0.262 | 0.012 | 0.274 | 0.014 | 0.287 | 0.021 | 0.282 | 0.022 |
| 7 T | 0.293 | 0.010 | 0.273 | 0.012 | 0.267 | 0.013 | 0.266 | 0.013 | |
| diff | −0.031 | 0.008 | 0.002 | 0.015 | 0.020 | 0.022 | 0.016 | 0.023 | |
| kMW [s−1] | 3 T | 6.11 | 0.56 | 6.04 | 0.54 | 5.41 | 0.57 | 5.55 | 0.63 |
| 7 T | 5.01 | 0.29 | 5.13 | 0.32 | 5.30 | 0.45 | 5.30 | 0.46 | |
| diff | 1.09 | 0.66 | 0.91 | 0.68 | 0.12 | 0.75 | 0.25 | 0.81 | |
| Residue | 3 T | 1.7E-5 | 2.0E-5 | 1.8E-5 | |||||
| 7 T | 0.6E-5 | 0.5E-5 | 0.5E-5 | ||||||