Figure 4.

Response of HCl-acidified canine blood to ROMB solutions composed of Na₂CO₃ and NaOH. Measured blood gas parameters (A) pH, (B) PCO₂, (C) [${\text{HCO}}_3^{-}$], and (D) [Na⁺] of HCl-CA-K9-2 acidified canine blood as a function of x_NaOH, the fraction of NaOH solution, in ROMB solutions having different proportions of 150 mM NaOH solution to 150 mM Na₂CO₃ solution. One part of the mixed solution is added to nine parts of acidified canine blood. Dashed lines represent parameter values of the acidified canine blood prior to adding the ROMB solution. Solid line in (A) is the average of the measured pH values; solid lines in (B–D) are linear least squares fits (see text for parameter values and uncertainties).