Figure 5.

Response of HCl-acidified canine blood to 1:1 solutions composed of NaHCO₃ and Na₂CO₃. Measured blood gas parameters (A) pH, (B) PCO₂, (C) [${\text{HCO}}_3^{-}$], and (D) [Na⁺] of HCl-CA-K9-2 acidified canine blood vs. concentration of carbonate species, [Carbonate], of equal volumes of aqueous solutions of equimolar NaHCO₃ and Na₂CO₃ (i.e., 1:1 proportions). One part of the mixed base solution is added to nine parts of acidified canine blood. In each panel, the reference parameter value of acidified blood without base treatment corresponds to the point at [Carbonate] = 0 mM and the dashed line. Values for [${\text{HCO}}_3^{-}$] and [Na⁺] at the highest concentration lie beyond the detection limits of the BGA.