Figure 8.

Titration of HCl-acidified canine blood by base solutions. Measured pH during titration of an initial volume of 4 mL of HCl-CA-K9-3 acidified canine blood using an added volume V_b of a base solution, 150 mM NaHCO₃ (squares), 100 mM Na₂CO₃ (circles), and 100 mM NaOH + 100 mM NaCl (triangles); Dashed line, pH = 7.4 reference level, showing that nearly 5 times the volume of 150 mM NaHCO₃ would be needed compared to 100 mM Na₂CO₃ solution to raise the pH of the blood to the reference level. The titration has been performed at 23°C.