Table 1.
Comparison of means for ICRU point doses and D2cc volume doses in bladder and rectum
| BT1 | Bladder | Rectum |
|---|---|---|
| Mean ICRU2 (Gy) | 2.9 (range: 1.2-4.5) | 3.4 (range: 2.4-4.2) |
| Mean D2cc3 (Gy) | 3.9 (range: 1.3-6.3) | 3.6 (range: 1.8-5.9) |
| Paired T-Test | P = 0.000, 95% CI (–1.18, –0.71) | P = 0.055, 95% CI (–0.41, 0.01) |
| Average Ratio (D2cc/ICRU) | 1.34 ± 0.34 | 1.07 ± 0.25 |
| EBRT4 + BT | Bladder | Rectum |
| Mean Total Dose using ICRU (GyEQD2) | 67.3 (range: 58.5-78.1) | 71.7 (range: 62.4-81.5) |
| Mean Total Dose using D2cc (GyEQD2) | 78.5 (range: 61.6-106.6) | 74.3 (range: 63.9-80.2) |
| Paired T-Test | P = 0.004, 95% CI (–17.89, –4.52) | P = 0.090, 95% CI (–5.74, 0.50) |
| Average Ratio (D2cc/ICRU) | 1.16 ± 0.12 | 1.04 ± 0.06 |
1
BT – Brachytherapy
2
ICRU – International Commission on Radiation Units and Measurements (ICRU defined point doses)
3
D2cc – Minimum dose to the most irradiated contiguous volume of 2cc
4
EBRT – External beam radiotherapy